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Persistence of Smoking-Induced Dysregulation of MiRNA Expression in the Small Airway Epithelium Despite Smoking Cessation

Even after quitting smoking, the risk of the development of chronic obstructive pulmonary disease (COPD) and lung cancer remains significantly higher compared to healthy nonsmokers. Based on the knowledge that COPD and most lung cancers start in the small airway epithelium (SAE), we hypothesized tha...

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Detalles Bibliográficos
Autores principales: Wang, Guoqing, Wang, Rui, Strulovici-Barel, Yael, Salit, Jacqueline, Staudt, Michelle R., Ahmed, Joumana, Tilley, Ann E., Yee-Levin, Jenny, Hollmann, Charleen, Harvey, Ben-Gary, Kaner, Robert J., Mezey, Jason G., Sridhar, Sriram, Pillai, Sreekumar G., Hilton, Holly, Wolff, Gerhard, Bitter, Hans, Visvanathan, Sudha, Fine, Jay S., Stevenson, Christopher S., Crystal, Ronald G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401720/
https://www.ncbi.nlm.nih.gov/pubmed/25886353
http://dx.doi.org/10.1371/journal.pone.0120824