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Up-Regulation of TREK-2 Potassium Channels in Cultured Astrocytes Requires De Novo Protein Synthesis: Relevance to Localization of TREK-2 Channels in Astrocytes after Transient Cerebral Ischemia

Excitotoxicity due to glutamate receptor over-activation is one of the key mediators of neuronal death after an ischemic insult. Therefore, a major function of astrocytes is to maintain low extracellular levels of glutamate. The ability of astrocytic glutamate transporters to regulate the extracellu...

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Detalles Bibliográficos
Autores principales: Rivera-Pagán, Aixa F., Rivera-Aponte, David E., Melnik-Martínez, Katya V., Zayas-Santiago, Astrid, Kucheryavykh, Lilia Y., Martins, Antonio H., Cubano, Luis A., Skatchkov, Serguei N., Eaton, Misty J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401746/
https://www.ncbi.nlm.nih.gov/pubmed/25886567
http://dx.doi.org/10.1371/journal.pone.0125195