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Loregic: A Method to Characterize the Cooperative Logic of Regulatory Factors

The topology of the gene-regulatory network has been extensively analyzed. Now, given the large amount of available functional genomic data, it is possible to go beyond this and systematically study regulatory circuits in terms of logic elements. To this end, we present Loregic, a computational meth...

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Detalles Bibliográficos
Autores principales: Wang, Daifeng, Yan, Koon-Kiu, Sisu, Cristina, Cheng, Chao, Rozowsky, Joel, Meyerson, William, Gerstein, Mark B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401777/
https://www.ncbi.nlm.nih.gov/pubmed/25884877
http://dx.doi.org/10.1371/journal.pcbi.1004132