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Endopeptidase-Mediated Beta Lactam Tolerance

In many bacteria, inhibition of cell wall synthesis leads to cell death and lysis. The pathways and enzymes that mediate cell lysis after exposure to cell wall-acting antibiotics (e.g. beta lactams) are incompletely understood, but the activities of enzymes that degrade the cell wall (‘autolysins’)...

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Detalles Bibliográficos
Autores principales: Dörr, Tobias, Davis, Brigid M., Waldor, Matthew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401780/
https://www.ncbi.nlm.nih.gov/pubmed/25884840
http://dx.doi.org/10.1371/journal.ppat.1004850