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A Redox Regulatory System Critical for Mycobacterial Survival in Macrophages and Biofilm Development

Survival of M. tuberculosis in host macrophages requires the eukaryotic-type protein kinase G, PknG, but the underlying mechanism has remained unknown. Here, we show that PknG is an integral component of a novel redox homeostatic system, RHOCS, which includes the ribosomal protein L13 and RenU, a Nu...

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Detalles Bibliográficos
Autores principales: Wolff, Kerstin A., de la Peña, Andres H., Nguyen, Hoa T., Pham, Thanh H., Amzel, L. Mario, Gabelli, Sandra B., Nguyen, Liem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401782/
https://www.ncbi.nlm.nih.gov/pubmed/25884716
http://dx.doi.org/10.1371/journal.ppat.1004839