Genetic and pharmacological analysis identifies a physiological role for the AHR in epidermal differentiation

Stimulation of the aryl hydrocarbon receptor (AHR) by xenobiotics is known to affect epidermal differentiation and skin barrier formation. The physiological role of endogenous AHR signaling in keratinocyte differentiation is not known. We used murine and human skin models to address the hypothesis t...

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Detalles Bibliográficos
Autores principales: van den Bogaard, Ellen, Podolsky, Michael, Smits, Jos, Cui, Xiao, John, Christian, Gowda, Krishne, Desai, Dhimant, Amin, Shantu, Schalkwijk, Joost, Perdew, Gary H., Glick, Adam B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402116/
https://www.ncbi.nlm.nih.gov/pubmed/25602157
http://dx.doi.org/10.1038/jid.2015.6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402116/
https://www.ncbi.nlm.nih.gov/pubmed/25602157
http://dx.doi.org/10.1038/jid.2015.6

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