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Smooth Muscle Specific Overexpression of p22(phox) Potentiates Carotid Artery Wall Thickening in Response to Injury
We hypothesized that transgenic mice overexpressing the p22(phox) subunit of the NADPH oxidase selectively in smooth muscle (Tg(p22smc)) would exhibit an exacerbated response to transluminal carotid injury compared to wild-type mice. To examine the role of reactive oxygen species (ROS) as a mediator...
Autores principales: | Manogue, Michael R., Bennett, Justin R., Holland, Drury S., Choi, Chung-Sik, Drake, Douglas A., Taylor, Mark S., Weber, David S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402189/ https://www.ncbi.nlm.nih.gov/pubmed/25945151 http://dx.doi.org/10.1155/2015/305686 |
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