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Modeling Maintenance of Long-Term Potentiation in Clustered Synapses: Long-Term Memory without Bistability

Memories are stored, at least partly, as patterns of strong synapses. Given molecular turnover, how can synapses maintain strong for the years that memories can persist? Some models postulate that biochemical bistability maintains strong synapses. However, bistability should give a bimodal distribut...

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Detalles Bibliográficos
Autor principal: Smolen, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402204/
https://www.ncbi.nlm.nih.gov/pubmed/25945261
http://dx.doi.org/10.1155/2015/185410