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GABA(B) receptor phosphorylation regulates KCTD12-induced K(+) current desensitization

GABA(B) receptors assemble from GABA(B)1 and GABA(B2) subunits. GABA(B2) additionally associates with auxiliary KCTD subunits (named after their K(+) channel tetramerization-domain). GABA(B) receptors couple to heterotrimeric G–proteins and activate inwardly-rectifying K(+) channels through the βγ s...

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Detalles Bibliográficos
Autores principales: Adelfinger, Lisa, Turecek, Rostislav, Ivankova, Klara, Jensen, Anders A., Moss, Stephen J., Gassmann, Martin, Bettler, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402209/
https://www.ncbi.nlm.nih.gov/pubmed/25065880
http://dx.doi.org/10.1016/j.bcp.2014.07.013