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HIV-1 matrix domain removal ameliorates virus assembly and processing defects incurred by positive nucleocapsid charge elimination

Human immunodeficiency virus type 1 nucleocapsid (NC) basic residues presumably contribute to virus assembly via RNA, which serves as a scaffold for Gag–Gag interaction during particle assembly. To determine whether NC basic residues play a role in Gag cleavage (thereby impacting virus assembly), Ga...

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Detalles Bibliográficos
Autores principales: Ko, Li-Jung, Yu, Fu-Hsien, Huang, Kuo-Jung, Wang, Chin-Tien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402288/
https://www.ncbi.nlm.nih.gov/pubmed/25905033
http://dx.doi.org/10.1016/j.fob.2015.04.003