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Characterization of a Novel Antisense RNA in the Major Pilin Locus of Neisseria meningitidis Influencing Antigenic Variation

Expression of type four pili (Tfp) is essential for virulence in Neisseria meningitidis. Pili mediate adhesion, bacterial aggregation, and DNA uptake. In N. meningitidis, the major pilin subunit is encoded by the pilE gene. In some strains, PilE is subject to phase and antigenic variation, which can...

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Detalles Bibliográficos
Autores principales: Tan, Felicia Y. Y., Wörmann, Mirka E., Loh, Edmund, Tang, Christoph M., Exley, Rachel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402397/
https://www.ncbi.nlm.nih.gov/pubmed/25755192
http://dx.doi.org/10.1128/JB.00082-15