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CYP7A1 Gene Polymorphism Located in the 5′ Upstream Region Modifies the Risk of Coronary Artery Disease

Background. 7-Alpha cholesterol hydroxylase (CYP7A1), the first enzyme of classic conversion pathway leading from cholesterol to bile acids synthesis, is encoded by CYP7A1 gene. Its single nucleotide polymorphisms (SNPs) influence serum lipid levels and may be related to impaired lipid profile leadi...

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Detalles Bibliográficos
Autores principales: Iwanicki, Tomasz, Balcerzyk, Anna, Niemiec, Pawel, Nowak, Tomasz, Ochalska-Tyka, Anna, Krauze, Jolanta, Kosiorz-Gorczynska, Sylwia, Grzeszczak, Wladyslaw, Zak, Iwona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402502/
https://www.ncbi.nlm.nih.gov/pubmed/25944972
http://dx.doi.org/10.1155/2015/185969