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Increased functional protein expression using nucleotide sequence features enriched in highly expressed genes in zebrafish

Many genetic manipulations are limited by difficulty in obtaining adequate levels of protein expression. Bioinformatic and experimental studies have identified nucleotide sequence features that may increase expression, however it is difficult to assess the relative influence of these features. Zebra...

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Detalles Bibliográficos
Autores principales: Horstick, Eric J., Jordan, Diana C., Bergeron, Sadie A., Tabor, Kathryn M., Serpe, Mihaela, Feldman, Benjamin, Burgess, Harold A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402511/
https://www.ncbi.nlm.nih.gov/pubmed/25628360
http://dx.doi.org/10.1093/nar/gkv035