Unwinding forward and sliding back: an intermittent unwinding mode of the BLM helicase

There are lines of evidence that the Bloom syndrome helicase, BLM, catalyzes regression of stalled replication forks and disrupts displacement loops (D-loops) formed during homologous recombination (HR). Here we constructed a forked DNA with a 3′ single-stranded gap and a 5′ double-stranded handle t...

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Detalles Bibliográficos
Autores principales: Wang, Shuang, Qin, Wei, Li, Jing-Hua, Lu, Ying, Lu, Ke-Yu, Nong, Da-Guan, Dou, Shuo-Xing, Xu, Chun-Hua, Xi, Xu-Guang, Li, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402530/
https://www.ncbi.nlm.nih.gov/pubmed/25765643
http://dx.doi.org/10.1093/nar/gkv209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402530/
https://www.ncbi.nlm.nih.gov/pubmed/25765643
http://dx.doi.org/10.1093/nar/gkv209

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