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Biflavone Ginkgetin, a Novel Wnt Inhibitor, Suppresses the Growth of Medulloblastoma

Medulloblastoma (MB) is a form of malignant brain tumor that predominantly arises in infants and children, of which approximately 25 % is due to upregulation of canonical Wnt pathway with mainly mutations in CTNNB1. Therefore, Wnt inhibitors could offer rational therapeutic strategies and chemopreve...

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Detalles Bibliográficos
Autores principales: Ye, Zhen-Nan, Yu, Mu-Yuan, Kong, Ling-Mei, Wang, Wei-Hua, Yang, Yuan-Feng, Liu, Jie-Qing, Qiu, Ming-Hua, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402583/
https://www.ncbi.nlm.nih.gov/pubmed/25821199
http://dx.doi.org/10.1007/s13659-015-0056-4