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A comparative study of disease genes and drug targets in the human protein interactome

BACKGROUND: Disease genes cause or contribute genetically to the development of the most complex diseases. Drugs are the major approaches to treat the complex disease through interacting with their targets. Thus, drug targets are critical for treatment efficacy. However, the interrelationship betwee...

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Detalles Bibliográficos
Autores principales: Sun, Jingchun, Zhu, Kevin, Zheng, W Jim, Xu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402590/
https://www.ncbi.nlm.nih.gov/pubmed/25861037
http://dx.doi.org/10.1186/1471-2105-16-S5-S1