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RNA chaperones buffer deleterious mutations in E. coli

Both proteins and RNAs can misfold into non-functional conformations. Protein chaperones promote native folding of nascent polypeptides and refolding of misfolded species, thereby buffering mutations that compromise protein structure and function. Here, we show that RNA chaperones can also act as mu...

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Detalles Bibliográficos
Autores principales: Rudan, Marina, Schneider, Dominique, Warnecke, Tobias, Krisko, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402597/
https://www.ncbi.nlm.nih.gov/pubmed/25806682
http://dx.doi.org/10.7554/eLife.04745