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Evaluation of the Dutch BRCA1/2 clinical genetic center referral criteria in an unselected early breast cancer population

In this study, we evaluated the diagnostic value of the Dutch Clinical Genetic Center (CGC) referral guidelines for BRCA1/2 mutation testing in 903 early breast cancer patients, unselected for family history, diagnosed in a cancer hospital before the age of 50 years in 1974–2002; most prevalent Dutc...

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Detalles Bibliográficos
Autores principales: van den Broek, Alexandra J, de Ruiter, Karen, van 't Veer, Laura J, Tollenaar, Rob A E M, van Leeuwen, Flora E, Verhoef, Senno, Schmidt, Marjanka K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402636/
https://www.ncbi.nlm.nih.gov/pubmed/25138101
http://dx.doi.org/10.1038/ejhg.2014.161