A non-canonical mechanism for Crm1-export cargo complex assembly

The transport receptor Crm1 mediates the export of diverse cargos containing leucine-rich nuclear export signals (NESs) through complex formation with RanGTP. To ensure efficient cargo release in the cytoplasm, NESs have evolved to display low affinity for Crm1. However, mechanisms that overcome low...

Descripción completa

Detalles Bibliográficos
Autores principales: Fischer, Ute, Schäuble, Nico, Schütz, Sabina, Altvater, Martin, Chang, Yiming, Boulos Faza, Marius, Panse, Vikram Govind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402694/
https://www.ncbi.nlm.nih.gov/pubmed/25895666
http://dx.doi.org/10.7554/eLife.05745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402694/
https://www.ncbi.nlm.nih.gov/pubmed/25895666
http://dx.doi.org/10.7554/eLife.05745

Ejemplares similares