Computer aided identification of sodium channel blockers in the clinical treatment of epilepsy using molecular docking tools

Phenytoin (PHT) and Carbamazepine (CBZ) are excellent sodium channel blockers administered in clinical treatment of epileptic seizures. However, the narrow therapeutic range and limited pharmacokinetics of these drugs have raised serious concerns in the proper management of epilepsy. To overcome thi...

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Detalles Bibliográficos
Autores principales: Shaheen, Uzma, Akka, Jyothy, Hinore, Jitendra Singh, Girdhar, Amandeep, Bandaru, Srinivas, Sumithnath, Tharaparambil Gangadharan, Nayarisseri, Anuraj, Munshi, Anjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2015
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403034/
https://www.ncbi.nlm.nih.gov/pubmed/25914447
http://dx.doi.org/10.6026/97320630011131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403034/
https://www.ncbi.nlm.nih.gov/pubmed/25914447
http://dx.doi.org/10.6026/97320630011131

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