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Metabolic and hypoxic adaptation to anti-angiogenic therapy: a target for induced essentiality
Anti-angiogenic therapy has increased the progression-free survival of many cancer patients but has had little effect on overall survival, even in colon cancer (average 6–8 weeks) due to resistance. The current licensed targeted therapies all inhibit VEGF signalling (Table1). Many mechanisms of resi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BlackWell Publishing Ltd
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403040/ https://www.ncbi.nlm.nih.gov/pubmed/25700172 http://dx.doi.org/10.15252/emmm.201404271 |