A DNA/HDAC dual-targeting drug CY190602 with significantly enhanced anticancer potency

Genotoxic drugs constitute a major treatment modality for human cancers; however, cancer cells' intrinsic DNA repair capability often increases the threshold of lethality and renders these drugs ineffective. The emerging roles of HDACs in DNA repair provide new opportunities for improving tradi...

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Detalles Bibliográficos
Autores principales: Liu, Chuan, Ding, Hongyu, Li, Xiaoxi, Pallasch, Christian P, Hong, Liya, Guo, Dianwu, Chen, Yi, Wang, Difei, Wang, Wei, Wang, Yajie, Hemann, Michael T, Jiang, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403045/
https://www.ncbi.nlm.nih.gov/pubmed/25759362
http://dx.doi.org/10.15252/emmm.201404580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403045/
https://www.ncbi.nlm.nih.gov/pubmed/25759362
http://dx.doi.org/10.15252/emmm.201404580

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