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A streptococcal lipid toxin induces membrane permeabilization and pyroptosis leading to fetal injury

Group B streptococci (GBS) are Gram-positive bacteria that cause infections in utero and in newborns. We recently showed that the GBS pigment is hemolytic and increased pigment production promotes bacterial penetration of human placenta. However, mechanisms utilized by the hemolytic pigment to induc...

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Detalles Bibliográficos
Autores principales: Whidbey, Christopher, Vornhagen, Jay, Gendrin, Claire, Boldenow, Erica, Samson, Jenny Mae, Doering, Kenji, Ngo, Lisa, Ezekwe, Ejiofor A D, Gundlach, Jens H, Elovitz, Michal A, Liggitt, Denny, Duncan, Joseph A, Adams Waldorf, Kristina M, Rajagopal, Lakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403049/
https://www.ncbi.nlm.nih.gov/pubmed/25750210
http://dx.doi.org/10.15252/emmm.201404883