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Stress Responses from the Endoplasmic Reticulum in Cancer

The endoplasmic reticulum (ER) is a dynamic organelle that is essential for multiple cellular functions. During cellular stress conditions, including nutrient deprivation and dysregulation of protein synthesis, unfolded/misfolded proteins accumulate in the ER lumen, resulting in activation of the un...

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Detalles Bibliográficos
Autores principales: Kato, Hironori, Nishitoh, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403295/
https://www.ncbi.nlm.nih.gov/pubmed/25941664
http://dx.doi.org/10.3389/fonc.2015.00093