Stabilization of G protein-coupled receptors by point mutations

G protein-coupled receptors (GPCRs) are flexible integral membrane proteins involved in transmembrane signaling. Their involvement in many physiological processes makes them interesting targets for drug development. Determination of the structure of these receptors will help to design more specific...

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Detalles Bibliográficos
Autores principales: Heydenreich, Franziska M., Vuckovic, Ziva, Matkovic, Milos, Veprintsev, Dmitry B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403299/
https://www.ncbi.nlm.nih.gov/pubmed/25941489
http://dx.doi.org/10.3389/fphar.2015.00082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403299/
https://www.ncbi.nlm.nih.gov/pubmed/25941489
http://dx.doi.org/10.3389/fphar.2015.00082

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