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CCCTC-Binding Factor Recruitment to the Early Region of the Human Papillomavirus 18 Genome Regulates Viral Oncogene Expression

Host cell differentiation-dependent regulation of human papillomavirus (HPV) gene expression is required for productive infection. The host cell CCCTC-binding factor (CTCF) functions in genome-wide chromatin organization and gene regulation. We have identified a conserved CTCF binding site in the E2...

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Detalles Bibliográficos
Autores principales: Paris, Christian, Pentland, Ieisha, Groves, Ian, Roberts, David C., Powis, Simon J., Coleman, Nicholas, Roberts, Sally, Parish, Joanna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403478/
https://www.ncbi.nlm.nih.gov/pubmed/25694598
http://dx.doi.org/10.1128/JVI.00097-15