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Copy number gain of granulin-epithelin precursor (GEP) at chromosome 17q21 associates with overexpression in human liver cancer

BACKGROUND: Granulin-epithelin precursor (GEP), a secretory growth factor, demonstrated overexpression in various human cancers, however, mechanism remain elusive. Primary liver cancer, hepatocellular carcinoma (HCC), ranks the second in cancer-related death globally. GEP controlled growth, invasion...

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Detalles Bibliográficos
Autores principales: Yung, Man Kuen, Lo, Kwok Wai, Yip, Chi Wai, Chung, Grace TY, Tong, Carol YK, Cheung, Phyllis FY, Cheung, Tan To, Poon, Ronnie TP, So, Samuel, Fan, Sheung Tat, Cheung, Siu Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403714/
https://www.ncbi.nlm.nih.gov/pubmed/25885205
http://dx.doi.org/10.1186/s12885-015-1294-x