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Methylation of RASSF1A gene promoter and the correlation with DNMT1 expression that may contribute to esophageal squamous cell carcinoma

BACKGROUND: Esophageal squamous cell carcinoma is one of the most common malignancies in the world. Studies have confirmed that there are many genes abnormally hypermethylated in esophageal squamous cell carcinoma. The objective is to detect methylation of the RASSF1A gene promoter and the expressio...

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Detalles Bibliográficos
Autores principales: Du, Zhenzong, Ma, Kui, Sun, Xiaolin, Li, Angui, Wang, Haiyong, Zhang, Lifei, Lin, Feng, Feng, Xiaoyan, Song, Jianfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403718/
https://www.ncbi.nlm.nih.gov/pubmed/25886188
http://dx.doi.org/10.1186/s12957-015-0557-y