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Oridonin stabilizes retinoic acid receptor alpha through ROS-activated NF-κB signaling

BACKGROUND: Retinoic acid receptor alpha (RARα) plays an essential role in the regulation of many biological processes, such as hematopoietic cell differentiation, while abnormal RARα function contributes to the pathogenesis of certain diseases including cancers, especially acute promyelocytic leuke...

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Detalles Bibliográficos
Autores principales: Cao, Yang, Wei, Wei, Zhang, Nan, Yu, Qing, Xu, Wen-Bin, Yu, Wen-Jun, Chen, Guo-Qiang, Wu, Ying-Li, Yan, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403721/
https://www.ncbi.nlm.nih.gov/pubmed/25886043
http://dx.doi.org/10.1186/s12885-015-1219-8