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Oridonin stabilizes retinoic acid receptor alpha through ROS-activated NF-κB signaling
BACKGROUND: Retinoic acid receptor alpha (RARα) plays an essential role in the regulation of many biological processes, such as hematopoietic cell differentiation, while abnormal RARα function contributes to the pathogenesis of certain diseases including cancers, especially acute promyelocytic leuke...
Autores principales: | Cao, Yang, Wei, Wei, Zhang, Nan, Yu, Qing, Xu, Wen-Bin, Yu, Wen-Jun, Chen, Guo-Qiang, Wu, Ying-Li, Yan, Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403721/ https://www.ncbi.nlm.nih.gov/pubmed/25886043 http://dx.doi.org/10.1186/s12885-015-1219-8 |
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