Cargando…

DNA methylation and histone modifications regulate SOX11 expression in lymphoid and solid cancer cells

BACKGROUND: The neural transcription factor SOX11 is present at specific stages during embryo development with a very restricted expression in adult tissue, indicating precise regulation of transcription. SOX11 is strongly up-regulated in some malignancies and have a functional role in tumorgenesis....

Descripción completa

Detalles Bibliográficos
Autores principales: Nordström, Lena, Andersson, Elin, Kuci, Venera, Gustavsson, Elin, Holm, Karolina, Ringnér, Markus, Guldberg, Per, Ek, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403777/
https://www.ncbi.nlm.nih.gov/pubmed/25880212
http://dx.doi.org/10.1186/s12885-015-1208-y