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DNA methylation and histone modifications regulate SOX11 expression in lymphoid and solid cancer cells
BACKGROUND: The neural transcription factor SOX11 is present at specific stages during embryo development with a very restricted expression in adult tissue, indicating precise regulation of transcription. SOX11 is strongly up-regulated in some malignancies and have a functional role in tumorgenesis....
Autores principales: | Nordström, Lena, Andersson, Elin, Kuci, Venera, Gustavsson, Elin, Holm, Karolina, Ringnér, Markus, Guldberg, Per, Ek, Sara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403777/ https://www.ncbi.nlm.nih.gov/pubmed/25880212 http://dx.doi.org/10.1186/s12885-015-1208-y |
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