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Experimental evaluation and computational modeling of the effects of encapsulation on the time-profile of glucose-stimulated insulin release of pancreatic islets

BACKGROUND: In type 1 diabetic patients, who have lost their ability to produce insulin, transplantation of pancreatic islet cells can normalize metabolic control in a manner that is not achievable with exogenous insulin. To be successful, this procedure has to address the problems caused by the imm...

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Detalles Bibliográficos
Autores principales: Buchwald, Peter, Cechin, Sirlene R, Weaver, Jessica D, Stabler, Cherie L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403786/
https://www.ncbi.nlm.nih.gov/pubmed/25889474
http://dx.doi.org/10.1186/s12938-015-0021-9