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Experimental evaluation and computational modeling of the effects of encapsulation on the time-profile of glucose-stimulated insulin release of pancreatic islets
BACKGROUND: In type 1 diabetic patients, who have lost their ability to produce insulin, transplantation of pancreatic islet cells can normalize metabolic control in a manner that is not achievable with exogenous insulin. To be successful, this procedure has to address the problems caused by the imm...
Autores principales: | Buchwald, Peter, Cechin, Sirlene R, Weaver, Jessica D, Stabler, Cherie L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403786/ https://www.ncbi.nlm.nih.gov/pubmed/25889474 http://dx.doi.org/10.1186/s12938-015-0021-9 |
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