Quantitative Assessment of Antibody Internalization with Novel Monoclonal Antibodies against Alexa Fluorophores

Antibodies against cell surface antigens may be internalized through their specific interactions with these proteins and in some cases may induce or perturb antigen internalization. The anti-cancer efficacy of antibody-drug conjugates is thought to rely on their uptake by cancer cells expressing the...

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Detalles Bibliográficos
Autores principales: Liao-Chan, Sindy, Daine-Matsuoka, Barbara, Heald, Nathan, Wong, Tiffany, Lin, Tracey, Cai, Allen G., Lai, Michelle, D’Alessio, Joseph A., Theunissen, Jan-Willem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403856/
https://www.ncbi.nlm.nih.gov/pubmed/25894652
http://dx.doi.org/10.1371/journal.pone.0124708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403856/
https://www.ncbi.nlm.nih.gov/pubmed/25894652
http://dx.doi.org/10.1371/journal.pone.0124708

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