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Quantitative Assessment of Antibody Internalization with Novel Monoclonal Antibodies against Alexa Fluorophores
Antibodies against cell surface antigens may be internalized through their specific interactions with these proteins and in some cases may induce or perturb antigen internalization. The anti-cancer efficacy of antibody-drug conjugates is thought to rely on their uptake by cancer cells expressing the...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403856/ https://www.ncbi.nlm.nih.gov/pubmed/25894652 http://dx.doi.org/10.1371/journal.pone.0124708 |