MAESTRO - multi agent stability prediction upon point mutations

BACKGROUND: Point mutations can have a strong impact on protein stability. A change in stability may subsequently lead to dysfunction and finally cause diseases. Moreover, protein engineering approaches aim to deliberately modify protein properties, where stability is a major constraint. In order to...

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Detalles Bibliográficos
Autores principales: Laimer, Josef, Hofer, Heidi, Fritz, Marko, Wegenkittl, Stefan, Lackner, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403899/
https://www.ncbi.nlm.nih.gov/pubmed/25885774
http://dx.doi.org/10.1186/s12859-015-0548-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403899/
https://www.ncbi.nlm.nih.gov/pubmed/25885774
http://dx.doi.org/10.1186/s12859-015-0548-6

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