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MAESTRO - multi agent stability prediction upon point mutations
BACKGROUND: Point mutations can have a strong impact on protein stability. A change in stability may subsequently lead to dysfunction and finally cause diseases. Moreover, protein engineering approaches aim to deliberately modify protein properties, where stability is a major constraint. In order to...
Autores principales: | Laimer, Josef, Hofer, Heidi, Fritz, Marko, Wegenkittl, Stefan, Lackner, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403899/ https://www.ncbi.nlm.nih.gov/pubmed/25885774 http://dx.doi.org/10.1186/s12859-015-0548-6 |
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