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AMDE-1 Is a Dual Function Chemical for Autophagy Activation and Inhibition

Autophagy is the process by which cytosolic components and organelles are delivered to the lysosome for degradation. Autophagy plays important roles in cellular homeostasis and disease pathogenesis. Small chemical molecules that can modulate autophagy activity may have pharmacological value for trea...

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Detalles Bibliográficos
Autores principales: Li, Min, Yang, Zuolong, Vollmer, Laura L., Gao, Ying, Fu, Yuanyuan, Liu, Cui, Chen, Xiaoyun, Liu, Peiqing, Vogt, Andreas, Yin, Xiao-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403922/
https://www.ncbi.nlm.nih.gov/pubmed/25894744
http://dx.doi.org/10.1371/journal.pone.0122083