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Effects of cyclin-dependent kinase inhibitor Purvalanol B application on protein expression and developmental progression in intra-erythrocytic Plasmodium falciparum parasites

BACKGROUND: The 2013 Malaria World Report indicated that in 2012 there were approximately 207 million cases of malaria, which resulted in an estimated 627,000 malaria-related deaths. Due to the alarming resistance of these parasites to traditional anti-malarial treatments there is a pressing need to...

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Detalles Bibliográficos
Autores principales: Bullard, Kristen M, Broccardo, Carolyn, Keenan, Susan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403934/
https://www.ncbi.nlm.nih.gov/pubmed/25879664
http://dx.doi.org/10.1186/s12936-015-0655-x