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MicroRNA-223 is a novel negative regulator of HSP90B1 in CLL
BACKGROUND: MicroRNAs are known to inhibit gene expression by binding to the 3′UTR of the target transcript. Downregulation of miR-223 has been recently reported to have prognostic significance in CLL. However, there is no evidence of the pathogenetic mechanism of this miRNA in CLL patients. METHODS...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404064/ https://www.ncbi.nlm.nih.gov/pubmed/25880332 http://dx.doi.org/10.1186/s12885-015-1212-2 |