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Polymorphisms in chloroquine resistance-associated genes in Plasmodium vivax in Ethiopia

BACKGROUND: Evidence for decreasing chloroquine (CQ) efficacy against Plasmodium vivax has been reported from many endemic countries in the world. In Ethiopia, P. vivax accounts for 40% of all malaria cases and CQ is the first-line drug for vivax malaria. Mutations in multidrug resistance 1 (pvmdr-1...

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Detalles Bibliográficos
Autores principales: Golassa, Lemu, Erko, Berhanu, Baliraine, Frederick N, Aseffa, Abraham, Swedberg, Göte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404130/
https://www.ncbi.nlm.nih.gov/pubmed/25889237
http://dx.doi.org/10.1186/s12936-015-0625-3