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Presence of High-Risk HPV mRNA in Relation to Future High-Grade Lesions among High-Risk HPV DNA Positive Women with Minor Cytological Abnormalities

OBJECTIVE: Continuous expression of E6- and E7-oncogenes of high-risk human papillomavirus (HPV) types is necessary for the development and maintenance of the dysplastic phenotype. The aim of the study was to determine the sensitivity and specificity of the APTIMA HPV mRNA assay (Hologic) in predict...

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Detalles Bibliográficos
Autores principales: Johansson, Hanna, Bjelkenkrantz, Kaj, Darlin, Lotten, Dilllner, Joakim, Forslund, Ola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404139/
https://www.ncbi.nlm.nih.gov/pubmed/25893988
http://dx.doi.org/10.1371/journal.pone.0124460