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SNAI2/SLUG and estrogen receptor mRNA expression are inversely correlated and prognostic of patient outcome in metastatic non-small cell lung cancer

BACKGROUND: Epithelial-mesenchymal transition (EMT) is involved in important malignant features of cancer cells, like invasion, metastatic potential, anti-apoptotic and stem-cell like phenotypes. Among several transcription factors, SNAI2/SLUG is supposed to play an essential role for EMT. METHODS:...

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Detalles Bibliográficos
Autores principales: Atmaca, Akin, Wirtz, Ralph W, Werner, Dominique, Steinmetz, Kristina, Claas, Silke, Brueckl, Wolfgang M, Jäger, Elke, Al-Batran, Salah-Eddin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404179/
https://www.ncbi.nlm.nih.gov/pubmed/25928859
http://dx.doi.org/10.1186/s12885-015-1310-1