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Mitochondrial regulation of β-cell function: maintaining the momentum for insulin release

All forms of diabetes share the common etiology of insufficient pancreatic β-cell function to meet peripheral insulin demand. In pancreatic β-cells, mitochondria serve to integrate the metabolism of exogenous nutrients into energy output, which ultimately leads to insulin release. As such, mitochond...

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Detalles Bibliográficos
Autores principales: Kaufman, Brett A., Li, Changhong, Soleimanpour, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404204/
https://www.ncbi.nlm.nih.gov/pubmed/25659350
http://dx.doi.org/10.1016/j.mam.2015.01.004