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A nucleotide-independent cyclic nitroxide label for monitoring segmental motions in nucleic acids

BACKGROUND: Spin labels, which are chemically stable radicals attached at specific sites of a bio-molecule, enable investigations on structure and dynamics of proteins and nucleic acids using techniques such as site-directed spin labeling and paramagnetic NMR. Among spin labels developed, the class...

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Detalles Bibliográficos
Autores principales: Nguyen, Phuong H, Popova, Anna M, Hideg, Kálmán, Qin, Peter Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404236/
https://www.ncbi.nlm.nih.gov/pubmed/25897395
http://dx.doi.org/10.1186/s13628-015-0019-5