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Site-specific programming of the host epithelial transcriptome by the gut microbiota

BACKGROUND: The intestinal epithelium separates us from the microbiota but also interacts with it and thus affects host immune status and physiology. Previous studies investigated microbiota-induced responses in the gut using intact tissues or unfractionated epithelial cells, thereby limiting conclu...

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Detalles Bibliográficos
Autores principales: Sommer, Felix, Nookaew, Intawat, Sommer, Nina, Fogelstrand, Per, Bäckhed, Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404278/
https://www.ncbi.nlm.nih.gov/pubmed/25887251
http://dx.doi.org/10.1186/s13059-015-0614-4