Targeted epigenome editing of an endogenous locus with chromatin modifiers is not stably maintained

BACKGROUND: DNA methylation and histone 3 lysine 9 (H3K9) methylation are considered as epigenetic marks that can be inherited through cell divisions. To explore the functional consequences and stability of these modifications, we employed targeted installment of DNA methylation and H3K9 methylation...

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Detalles Bibliográficos
Autores principales: Kungulovski, Goran, Nunna, Suneetha, Thomas, Maria, Zanger, Ulrich M, Reinhardt, Richard, Jeltsch, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404288/
https://www.ncbi.nlm.nih.gov/pubmed/25901185
http://dx.doi.org/10.1186/s13072-015-0002-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404288/
https://www.ncbi.nlm.nih.gov/pubmed/25901185
http://dx.doi.org/10.1186/s13072-015-0002-z

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