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Cytosolic Phospholipase A2 Modulates TLR2 Signaling in Synoviocytes

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic synovitis leading to destruction of cartilage and bone. PLA2 enzymes are key players in inflammation regulating the release of unsaturated fatty acids such as arachidonic acid (AA), a precursor of pro-inflammatory eicosanoid...

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Detalles Bibliográficos
Autores principales: Sommerfelt, Randi M., Feuerherm, Astrid J., Skuland, Trine, Johansen, Berit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404349/
https://www.ncbi.nlm.nih.gov/pubmed/25893499
http://dx.doi.org/10.1371/journal.pone.0119088