Cargando…
Cytosolic Phospholipase A2 Modulates TLR2 Signaling in Synoviocytes
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic synovitis leading to destruction of cartilage and bone. PLA2 enzymes are key players in inflammation regulating the release of unsaturated fatty acids such as arachidonic acid (AA), a precursor of pro-inflammatory eicosanoid...
Autores principales: | Sommerfelt, Randi M., Feuerherm, Astrid J., Skuland, Trine, Johansen, Berit |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404349/ https://www.ncbi.nlm.nih.gov/pubmed/25893499 http://dx.doi.org/10.1371/journal.pone.0119088 |
Ejemplares similares
-
Cytosolic Phospholipase A2 Regulates TNF-Induced Production of Joint Destructive Effectors in Synoviocytes
por: Sommerfelt, Randi M., et al.
Publicado: (2013) -
Cytosolic Phospholipase A2 Alpha Regulates TLR Signaling and Migration in Metastatic 4T1 Cells
por: Tunset, Hanna Maja, et al.
Publicado: (2019) -
Inhibition of Cytosolic Phospholipase A2α Induces Apoptosis in Multiple Myeloma Cells
por: Mahammad, Nur, et al.
Publicado: (2021) -
Cytosolic group IVA phospholipase A2 inhibitors, AVX001 and AVX002, ameliorate collagen-induced arthritis
por: Feuerherm, A. J., et al.
Publicado: (2019) -
Anti-vascular effects of the cytosolic phospholipase A2 inhibitor AVX235 in a patient-derived basal-like breast cancer model
por: Kim, Eugene, et al.
Publicado: (2016)