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TDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets
Therapeutic options for patients with amyotrophic lateral sclerosis (ALS) are currently limited. However, recent studies show that almost all cases of ALS, as well as tau-negative frontotemporal dementia (FTD), share a common neuropathology characterized by the deposition of TAR-DNA binding protein...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404432/ https://www.ncbi.nlm.nih.gov/pubmed/25652699 http://dx.doi.org/10.1007/s13311-015-0338-x |